QuikChange Multi Site-Directed Mutagenesis Kit, Part Number 200531

Hazard statements (CLP)

H227, H317, H318, H319, H361, H412

Code

Statements

H227

Combustible liquid

2.1 Classification of the substance or mixture

QuikSolution H227 FLAMMABLE LIQUIDS - Category 4 10X QuikChange Multi Reaction Buffer H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A XL10-Gold 2-Mercaptoethanol H318 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 1 H317 SKIN SENSITISATION - Category 1 H361 REPRODUCTIVE TOXICITY - Category 2 H412 LONG-TERM (CHRONIC) AQUATIC HAZARD - Category 3 dNTP Mix Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 5.7%

Hazard pictograms

10X QuikChange Multi Reaction Buffer XL10-Gold 2-Mercaptoethanol

Signal word

QuikSolution WARNING QuikChange Multi Enzyme No signal word. Blend 10X QuikChange Multi WARNING Reaction Buffer dNTP Mix No signal word. Dpn I No signal word. QuikChange Multi Control No signal word. Template QuikChange Multi Ctl. No signal word. Primer Mix XL10-Gold Ultracompetent No signal word. cells XL10-Gold DANGER 2-Mercaptoethanol pUC 18 DNA Control Plasmid No signal word.

Hazard statements

QuikSolution H227 - Combustible liquid. QuikChange Multi Enzyme No known significant effects or critical hazards. Blend 10X QuikChange Multi H319 - Causes serious eye irritation. Reaction Buffer dNTP Mix No known significant effects or critical hazards. Dpn I No known significant effects or critical hazards. QuikChange Multi Control No known significant effects or critical hazards. Template QuikChange Multi Ctl. No known significant effects or critical hazards. Primer Mix XL10-Gold Ultracompetent No known significant effects or critical hazards. cells XL10-Gold H317 - May cause an allergic skin reaction. 2-Mercaptoethanol H318 - Causes serious eye damage. H361 - Suspected of damaging fertility or the unborn child. H412 - Harmful to aquatic life with long lasting effects. pUC 18 DNA Control Plasmid No known significant effects or critical hazards.

Prevention

QuikSolution P210 - Keep away from flames and hot surfaces. No smoking. QuikChange Multi Enzyme Not applicable. Blend 10X QuikChange Multi P280 - Wear eye or face protection. Reaction Buffer dNTP Mix Not applicable. Dpn I Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Not applicable. Primer Mix XL10-Gold Ultracompetent Not applicable. cells XL10-Gold P201 - Obtain special instructions before use. 2-Mercaptoethanol P281 - Use personal protective equipment as required. P280 - Wear protective gloves. Wear eye or face protection. pUC 18 DNA Control Plasmid Not applicable.

Response

QuikSolution Not applicable. QuikChange Multi Enzyme Not applicable. Blend 10X QuikChange Multi P305 + P351 + P338 - IF IN EYES: Rinse cautiously Reaction Buffer with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical advice or attention. dNTP Mix Not applicable. Dpn I Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Not applicable. Primer Mix XL10-Gold Ultracompetent Not applicable. cells XL10-Gold P305 + P351 + P338, P310 - IF IN EYES: Rinse 2-Mercaptoethanol cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or doctor. pUC 18 DNA Control Plasmid Not applicable.

Storage

QuikSolution P403 + P235 - Store in a well-ventilated place. Keep cool. QuikChange Multi Enzyme Not applicable. Blend 10X QuikChange Multi Not applicable. Reaction Buffer dNTP Mix Not applicable. Dpn I Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Not applicable. Primer Mix XL10-Gold Ultracompetent Not applicable. cells XL10-Gold Not applicable. 2-Mercaptoethanol pUC 18 DNA Control Plasmid Not applicable.

Disposal

QuikSolution P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. QuikChange Multi Enzyme Not applicable. Blend 10X QuikChange Multi Not applicable. Reaction Buffer dNTP Mix Not applicable. Dpn I Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Not applicable. Primer Mix XL10-Gold Ultracompetent Not applicable. cells XL10-Gold P501 - Dispose of contents and container in 2-Mercaptoethanol accordance with all local, regional, national and international regulations. pUC 18 DNA Control Plasmid Not applicable.

Supplemental label elements

elements Additional warning : QuikSolution Not applicable. phrases QuikChange Multi Enzyme Not applicable. Blend 10X QuikChange Multi Not applicable. Reaction Buffer dNTP Mix Not applicable. Dpn I Not applicable. QuikChange Multi Control Not applicable. Template QuikChange Multi Ctl. Not applicable. Primer Mix XL10-Gold Ultracompetent Not applicable. cells XL10-Gold Not applicable. 2-Mercaptoethanol pUC 18 DNA Control Plasmid Not applicable. Other hazards which do not : QuikSolution None known. result in classification QuikChange Multi Enzyme None known. Blend 10X QuikChange Multi None known. Reaction Buffer dNTP Mix None known. Dpn I None known. QuikChange Multi Control None known. Template QuikChange Multi Ctl. None known. Primer Mix XL10-Gold Ultracompetent None known. cells XL10-Gold None known. 2-Mercaptoethanol pUC 18 DNA Control Plasmid None known.