QuikChange II Site-Directed Mutagenesis Kit, Part Number 200523

Agilent Technologies Australia Pty Ltd

Revision date : 2019-03-29

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GHS07
Health risk rating 2
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

56-81-5

Name of the chemical

glycerol

Concentration

N/A

EC/CAS

67-68-5

Name of the chemical

dimethyl sulphoxide

Concentration

N/A

EC/CAS

9002-93-1

Name of the chemical

Octylphenolethoxylates (OPEO)

Concentration

N/A

EC/CAS

57-50-1

Name of the chemical

Sucrose, pure C12H22O11

Concentration

N/A

General Information

Revision date

2019-03-29

Product name

QuikChange II Site-Directed Mutagenesis Kit, Part Number 200523

Emergency telephone

+(61)-290372994

Icons in SDS

Company Information

company name

Agilent Technologies Australia Pty Ltd

GHS Information

Signal word

Warning

Hazard Codes

Hazard statements (CLP)

H319

Hazard statements

Code

Statements

H319

Causes serious eye irritation

Section 2

2.1 Classification of the substance or mixture

10X Reaction Buffer H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A PfuUltra HF DNA Percentage of the mixture consisting of ingredient(s) Polymerase of unknown acute inhalation toxicity: 30 - 60% 10X Reaction Buffer Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% Dpn I Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% dNTP Mix Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% XL1-Blue supercompetent Percentage of the mixture consisting of ingredient(s) cells of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 10 - 30% 10X Reaction Buffer Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 3.2% dNTP Mix Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 5.7%

Hazard pictograms

10X Reaction Buffer

Signal word

PfuUltra HF DNA No signal word. Polymerase 10X Reaction Buffer WARNING Dpn I No signal word. Control Primer 1 (34-mer) No signal word. Control Primer 2 (34-mer) No signal word. pWS4.5 Control Template No signal word. dNTP Mix No signal word. XL1-Blue supercompetent No signal word. cells pUC 18 DNA Control Plasmid No signal word.

Hazard statements

PfuUltra HF DNA No known significant effects or critical hazards. Polymerase 10X Reaction Buffer H319 - Causes serious eye irritation. Dpn I No known significant effects or critical hazards. Control Primer 1 (34-mer) No known significant effects or critical hazards. Control Primer 2 (34-mer) No known significant effects or critical hazards. pWS4.5 Control Template No known significant effects or critical hazards. dNTP Mix No known significant effects or critical hazards. XL1-Blue supercompetent No known significant effects or critical hazards. cells pUC 18 DNA Control Plasmid No known significant effects or critical hazards.

Prevention

PfuUltra HF DNA Not applicable. Polymerase 10X Reaction Buffer P280 - Wear eye or face protection. P264 - Wash hands thoroughly after handling. Dpn I Not applicable. Control Primer 1 (34-mer) Not applicable. Control Primer 2 (34-mer) Not applicable. pWS4.5 Control Template Not applicable. dNTP Mix Not applicable. XL1-Blue supercompetent Not applicable. cells pUC 18 DNA Control Plasmid Not applicable.

Response

PfuUltra HF DNA Not applicable. Polymerase 10X Reaction Buffer P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Dpn I Not applicable. Control Primer 1 (34-mer) Not applicable. Control Primer 2 (34-mer) Not applicable. pWS4.5 Control Template Not applicable. dNTP Mix Not applicable. XL1-Blue supercompetent Not applicable. cells pUC 18 DNA Control Plasmid Not applicable.

Storage

PfuUltra HF DNA Not applicable. Polymerase 10X Reaction Buffer Not applicable. Dpn I Not applicable. Control Primer 1 (34-mer) Not applicable. Control Primer 2 (34-mer) Not applicable. pWS4.5 Control Template Not applicable. dNTP Mix Not applicable. XL1-Blue supercompetent Not applicable. cells pUC 18 DNA Control Plasmid Not applicable.

Disposal

PfuUltra HF DNA Not applicable. Polymerase 10X Reaction Buffer Not applicable. Dpn I Not applicable. Control Primer 1 (34-mer) Not applicable. Control Primer 2 (34-mer) Not applicable. pWS4.5 Control Template Not applicable. dNTP Mix Not applicable. XL1-Blue supercompetent Not applicable. cells pUC 18 DNA Control Plasmid Not applicable.

Supplemental label elements

elements Additional warning : PfuUltra HF DNA Not applicable. phrases Polymerase 10X Reaction Buffer Not applicable. Dpn I Not applicable. Control Primer 1 (34-mer) Not applicable. Control Primer 2 (34-mer) Not applicable. pWS4.5 Control Template Not applicable. dNTP Mix Not applicable. XL1-Blue supercompetent Not applicable. cells pUC 18 DNA Control Plasmid Not applicable. Other hazards which do not : PfuUltra HF DNA None known. result in classification Polymerase 10X Reaction Buffer None known. Dpn I None known. Control Primer 1 (34-mer) None known. Control Primer 2 (34-mer) None known. pWS4.5 Control Template None known. dNTP Mix None known. XL1-Blue supercompetent None known. cells pUC 18 DNA Control Plasmid None known.

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