GenetiSure Pre-Screen Amplification and Labeling Kit, Part Number 5190-7731

Hazard statements (CLP)

H302, H314, H315, H318, H319, H335, H402, H412

Code

Statements

H302

Harmful if swallowed

2.1 Classification of the substance or mixture

Buffer DLB H302 ACUTE TOXICITY (oral) - Category 4 H314 SKIN CORROSION/IRRITATION - Category 1 H318 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 1 DTT H302 ACUTE TOXICITY (oral) - Category 4 H315 SKIN CORROSION/IRRITATION - Category 2 H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A H335 SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE (Respiratory tract irritation) - Category 3 H402 SHORT-TERM (ACUTE) AQUATIC HAZARD - Category 3 H412 LONG-TERM (CHRONIC) AQUATIC HAZARD - Category 3 Amplification Reaction Buffer H315 SKIN CORROSION/IRRITATION - Category 2 H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A 5X gDNA Reaction Buffer Percentage of the mixture consisting of ingredient(s) of unknown dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown inhalation toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown oral toxicity: 1 - 10% Exo(-) Klenow Percentage of the mixture consisting of ingredient(s) of unknown inhalation toxicity: 30 - 60% DTT Percentage of the mixture consisting of ingredient(s) of unknown dermal toxicity: 10 - 30% Percentage of the mixture consisting of ingredient(s) of unknown inhalation toxicity: 10 - 30% Amplification Reaction Buffer Percentage of the mixture consisting of ingredient(s) of unknown inhalation toxicity: 1 - 10% 5X gDNA Reaction Buffer Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 3.2%

Hazard pictograms

Buffer DLB DTT Amplification Reaction Buffer

Signal word

Nuclease Free Water No signal word. Random Primers No signal word. 5X gDNA Reaction Buffer No signal word. Exo(-) Klenow No signal word. 10X dNTP Mix No signal word. Cyanine-3-dUTP No signal word. Cyanine-5-dUTP No signal word. Buffer DLB DANGER DTT WARNING Stop Solution No signal word. Amplification Reaction Buffer WARNING Amplification DNA No signal word. Polymerase PBS No signal word.

Hazard statements

Nuclease Free Water No known significant effects or critical hazards. Random Primers No known significant effects or critical hazards. 5X gDNA Reaction Buffer No known significant effects or critical hazards. Exo(-) Klenow No known significant effects or critical hazards. 10X dNTP Mix No known significant effects or critical hazards. Cyanine-3-dUTP No known significant effects or critical hazards. Cyanine-5-dUTP No known significant effects or critical hazards. Buffer DLB H302 - Harmful if swallowed. H314 - Causes severe skin burns and eye damage. DTT H302 - Harmful if swallowed. H319 - Causes serious eye irritation. H315 - Causes skin irritation. H335 - May cause respiratory irritation. H412 - Harmful to aquatic life with long lasting effects. Stop Solution No known significant effects or critical hazards. Amplification Reaction Buffer H319 - Causes serious eye irritation. H315 - Causes skin irritation. Amplification DNA No known significant effects or critical hazards. Polymerase PBS No known significant effects or critical hazards.

Prevention

Nuclease Free Water Not applicable. Random Primers Not applicable. 5X gDNA Reaction Buffer Not applicable. Exo(-) Klenow Not applicable. 10X dNTP Mix Not applicable. Cyanine-3-dUTP Not applicable. Cyanine-5-dUTP Not applicable. Buffer DLB P280 - Wear protective gloves. Wear eye or face protection. Wear protective clothing. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. DTT P280 - Wear protective gloves. Wear eye or face protection. P271 - Use only outdoors or in a well-ventilated area. P273 - Avoid release to the environment. P261 - Avoid breathing vapour. P270 - Do not eat, drink or smoke when using this product. P264 - Wash hands thoroughly after handling. Stop Solution Not applicable. Amplification Reaction Buffer P280 - Wear protective gloves. Wear eye or face protection. P264 - Wash hands thoroughly after handling. Amplification DNA Not applicable. Polymerase PBS Not applicable.

Response

Nuclease Free Water Not applicable. Random Primers Not applicable. 5X gDNA Reaction Buffer Not applicable. Exo(-) Klenow Not applicable. 10X dNTP Mix Not applicable. Cyanine-3-dUTP Not applicable. Cyanine-5-dUTP Not applicable. Buffer DLB P304 + P340 + P310 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Immediately call a POISON CENTER or physician. P301 + P310 + P330 + P331 - IF SWALLOWED: Immediately call a POISON CENTER or physician. Rinse mouth. Do NOT induce vomiting. P303 + P361 + P353 + P363 + P310 - IF ON SKIN (or hair): Take off immediately all contaminated clothing. Rinse skin with water or shower. Wash contaminated clothing before reuse. Immediately call a POISON CENTER or physician. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or physician. DTT P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P301 + P312 + P330 - IF SWALLOWED: Call a POISON CENTER or physician if you feel unwell. Rinse mouth. P302 + P352 + P362 + P363 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. Wash contaminated clothing before reuse. P332 + P313 - If skin irritation occurs: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Stop Solution Not applicable. Amplification Reaction Buffer P302 + P352 + P362 + P363 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. Wash contaminated clothing before reuse. P332 + P313 - If skin irritation occurs: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. Amplification DNA Not applicable. Polymerase PBS Not applicable.

Storage

Nuclease Free Water Not applicable. Random Primers Not applicable. 5X gDNA Reaction Buffer Not applicable. Exo(-) Klenow Not applicable. 10X dNTP Mix Not applicable. Cyanine-3-dUTP Not applicable. Cyanine-5-dUTP Not applicable. Buffer DLB P405 - Store locked up. DTT P405 - Store locked up. Stop Solution Not applicable. Amplification Reaction Buffer Not applicable. Amplification DNA Not applicable. Polymerase PBS Not applicable.

Disposal

Nuclease Free Water Not applicable. Random Primers Not applicable. 5X gDNA Reaction Buffer Not applicable. Exo(-) Klenow Not applicable. 10X dNTP Mix Not applicable. Cyanine-3-dUTP Not applicable. Cyanine-5-dUTP Not applicable. Buffer DLB P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. DTT P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. Stop Solution Not applicable. Amplification Reaction Buffer Not applicable. Amplification DNA Not applicable. Polymerase PBS Not applicable.

Supplemental label elements

Nuclease Free Water Not applicable. elements Random Primers Not applicable. 5X gDNA Reaction Buffer Not applicable. Exo(-) Klenow Not applicable. 10X dNTP Mix Not applicable. Cyanine-3-dUTP Not applicable. Cyanine-5-dUTP Not applicable. Buffer DLB Not applicable. DTT Not applicable. Stop Solution Not applicable. Amplification Reaction Buffer Not applicable. Amplification DNA Not applicable. Polymerase PBS Not applicable. Other hazards which do not : Nuclease Free Water None known. result in classification Random Primers None known. 5X gDNA Reaction Buffer None known. Exo(-) Klenow None known. 10X dNTP Mix None known. Cyanine-3-dUTP None known. Cyanine-5-dUTP None known. Buffer DLB Causes digestive tract burns. DTT None known. Stop Solution None known. Amplification Reaction Buffer None known. Amplification DNA None known. Polymerase PBS None known.