Gene Expression Hybridization Kit, Part Number 5188-5242

Hazard statements (CLP)

H315, H318, H319, H335, H373, H412

Code

Statements

H315

Causes skin irritation

2.1 Classification of the substance or mixture

10X Gene Expression Blocking Agent H315 SKIN CORROSION/IRRITATION - Category 2 H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A H335 SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE (Respiratory tract irritation) - Category 3 2X GEx Hyb Buffer (HI-RPM) H315 SKIN CORROSION/IRRITATION - Category 2 H318 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 1 H335 SPECIFIC TARGET ORGAN TOXICITY - SINGLE EXPOSURE (Respiratory tract irritation) - Category 3 H373 SPECIFIC TARGET ORGAN TOXICITY - REPEATED EXPOSURE (cardiovascular system, central nervous system (CNS), kidneys, thyroid) - Category 2 H412 LONG-TERM (CHRONIC) AQUATIC HAZARD - Category 3 25X Fragmentation Buffer H315 SKIN CORROSION/IRRITATION - Category 2 H319 SERIOUS EYE DAMAGE/EYE IRRITATION - Category 2A 10X Gene Expression Percentage of the mixture consisting of ingredient(s) Blocking Agent of unknown acute dermal toxicity: 10 - 30% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 30 - 60% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 10 - 30% 2X GEx Hyb Buffer (HI-RPM) Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 10 - 30% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 10 - 30% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 10 - 30% 25X Fragmentation Buffer Percentage of the mixture consisting of ingredient(s) of unknown acute dermal toxicity: 1 - 10% Percentage of the mixture consisting of ingredient(s) of unknown acute inhalation toxicity: 10 - 30% Percentage of the mixture consisting of ingredient(s) of unknown acute oral toxicity: 1 - 10% 10X Gene Expression Percentage of the mixture consisting of ingredient(s) Blocking Agent of unknown hazards to the aquatic environment: 30% 2X GEx Hyb Buffer (HI-RPM) Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 17.9% 25X Fragmentation Buffer Percentage of the mixture consisting of ingredient(s) of unknown hazards to the aquatic environment: 7.3%

Hazard pictograms

10X Gene Expression Blocking Agent 2X GEx Hyb Buffer (HI-RPM) 25X Fragmentation Buffer

Signal word

10X Gene Expression WARNING Blocking Agent 2X GEx Hyb Buffer (HI-RPM) DANGER 25X Fragmentation Buffer WARNING

Hazard statements

10X Gene Expression H319 - Causes serious eye irritation. Blocking Agent H315 - Causes skin irritation. H335 - May cause respiratory irritation. 2X GEx Hyb Buffer (HI-RPM) H318 - Causes serious eye damage. H315 - Causes skin irritation. H335 - May cause respiratory irritation. H373 - May cause damage to organs through prolonged or repeated exposure. (cardiovascular system, central nervous system (CNS), kidneys, thyroid) H412 - Harmful to aquatic life with long lasting effects. 25X Fragmentation Buffer H319 - Causes serious eye irritation. H315 - Causes skin irritation.

Prevention

10X Gene Expression P280 - Wear protective gloves. Wear eye or face Blocking Agent protection. P271 - Use only outdoors or in a well-ventilated area. P261 - Avoid breathing dust. P264 - Wash hands thoroughly after handling. 2X GEx Hyb Buffer (HI-RPM) P280 - Wear protective gloves. Wear eye or face protection. P271 - Use only outdoors or in a well-ventilated area. P273 - Avoid release to the environment. P260 - Do not breathe vapour. P264 - Wash hands thoroughly after handling. 25X Fragmentation Buffer P280 - Wear protective gloves. Wear eye or face protection. P264 - Wash hands thoroughly after handling.

Response

10X Gene Expression P304 + P340 + P312 - IF INHALED: Remove victim Blocking Agent to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P302 + P352 + P362 + P363 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. Wash contaminated clothing before reuse. P332 + P313 - If skin irritation occurs: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention. 2X GEx Hyb Buffer (HI-RPM) P314 - Get medical attention if you feel unwell. P304 + P340 + P312 - IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. Call a POISON CENTER or physician if you feel unwell. P302 + P352 + P362 + P363 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. Wash contaminated clothing before reuse. P332 + P313 - If skin irritation occurs: Get medical attention. P305 + P351 + P338 + P310 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. Immediately call a POISON CENTER or physician. 25X Fragmentation Buffer P302 + P352 + P362 + P363 - IF ON SKIN: Wash with plenty of soap and water. Take off contaminated clothing. Wash contaminated clothing before reuse. P332 + P313 - If skin irritation occurs: Get medical attention. P305 + P351 + P338 - IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337 + P313 - If eye irritation persists: Get medical attention.

Storage

10X Gene Expression P405 - Store locked up. Blocking Agent 2X GEx Hyb Buffer (HI-RPM) P405 - Store locked up. 25X Fragmentation Buffer Not applicable.

Disposal

10X Gene Expression P501 - Dispose of contents and container in Blocking Agent accordance with all local, regional, national and international regulations. 2X GEx Hyb Buffer (HI-RPM) P501 - Dispose of contents and container in accordance with all local, regional, national and international regulations. 25X Fragmentation Buffer Not applicable.

Supplemental label elements

elements Additional warning : 10X Gene Expression Not applicable. phrases Blocking Agent 2X GEx Hyb Buffer (HI-RPM) Not applicable. 25X Fragmentation Buffer Not applicable. Other hazards which do not : 10X Gene Expression None known. result in classification Blocking Agent 2X GEx Hyb Buffer (HI-RPM) None known. 25X Fragmentation Buffer None known.