HCMV (AD169 Strain) Purified Virus

SECTION 2: Hazards identification

OSHA Classification of the substance or mixture

Hazard pictograms

Not Regulated

Signal word

Not Regulated

Hazardous Ingredients

None

Hazard statements

Not Regulated

2.3 Other hazards

This preparation of HCMV is a BIOHAZARDOUS material containing ACTIVE VIRUS and should be handled in accordance with biosafety guidelines defined in the BMBL, NIH-CDC HHS Publication No. (CDC) 21-1112. Category: WHO Risk Group 2 Emergency Overview: Biohazardous Pathogenicity: Cytomegalovirus (CMV) infection is common and usually asymptomatic in healthy children and adults, but can cause severe disease in newborns and immunocompromised children or adults. CMV is the most common cause of congenital infection, affecting 0.2-2.4% of all infants, and also of viral-based mental retardation and hearing deficit in children of developing countries. Infections are often recurrent, caused by reactivation of latent virus (especially in immunocompromised patients such as bone marrow or other transplant recipients), reinfection may also occur due to the antigenic diversity of the virus. Infection may cause a mononucleosis-like syndrome with prolonged fever (lasting 2-3 weeks), malaise, atypical lymphocytosis, cervical lymphadenitis, mild hepatitis and encephalitis. (Original Pathogen Safety Data Sheet and Risk Assessment located at publichealth.gc.ca) Host Range: Humans.

PBT Substances

Not applicable

vPvB Substances

Not applicable

2.1 Classification of the substance or mixture

Classification according to Regulation (EC) No 1272/2008 This product is not classified as hazardous according to the Regulation (EC) No 1272/2008 and subsequent amendments. This product is not classified as hazardous according to the Globally Harmonized System (GHS) This product is not classified as hazardous according to OSHA GHS regulations within the U.S.