Replication-Defective Lentiviral Vectors

SECTION 2: Hazards identification

Hazard Classification This product CANNOT be classified in accordance with the Globally Harmonized System of Classification and Labelling (GHS) as it is a biological material and is outside the scope of this system The toxicological properties of this material have not been fully investigated As with any chemical product of unknown toxicity, take precautions to prevent contact with eye, skin and mucous membranes. Use good industrial hygiene practices to prevent accidental exposure. Product should only be handled by technically qualified individuals who are educated in handling chemicals of unknown toxicity This product should be handled as a biohazardous material under Biosafety Level 2/Enhanced Biosafety Level 2 Containment. Contact your local institutional biosafety office for accurate regional information

Hazard pictograms

Not applicable

Signal word

Not applicable

Hazard statements

None

Prevention

Obtain special instructions before use. Do not handle until all safety precautions have been read and understood. Do not get in eyes, on skin, or on clothing. Wash hands thoroughly after handling. Do not eat, drink or smoke when using this product. Wear protective gloves, eye protection, face protection, and protective clothing. Contaminated clothing must not be allowed out of the workplace. 2.

Response

If on skin Wash with plenty of soap and water. If skin irritation occurs Get medical advice/attention Take off contaminated clothing and wash before reuse. If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. If eye irritation persists: Get medical advice/attention. If inhaled: Remove person to fresh air and keep comfortable for breathing. Call a poison center or doctor if you feel unwell. If swallowed: Immediately call a poison center or doctor. Do NOT induce vomiting.

Storage

Store locked up. Store in accordance with Biosafety Level 2/Enhanced Biosafety Level 2 Containment requirements.

Disposal

Dispose of contents/container in accordance with manufacturer’s instructions. (See Section 13 of this SDS.)

2.3 Other hazards

Replication-defective lentiviral vectors are not known to cause disease in humans or animals. However, lentiviruses can integrate into the host cell genome and may pose some risk of insertional mutagenesis. Specific Concentration Limits The values listed below represent the percentages of ingredients of unknown toxicity. Acute oral toxicity <5% Acute dermal toxicity <5% Acute inhalation toxicity <5% Acute aquatic toxicity <5%

2.1 Classification of the substance or mixture

This product CANNOT be classified in accordance with the Globally Harmonized System of Classification and Labelling (GHS) as it is a biological material and is outside the scope of this system. The toxicological properties of this material have not been fully investigated. As with any chemical product of unknown toxicity, take precautions to prevent contact with eye, skin and mucous membranes. Use good industrial hygiene practices to prevent accidental exposure. Product should only be handled by technically qualified individuals who are educated in handling chemicals of unknown toxicity. This product should be handled as a biohazardous material under Biosafety Level 2/Enhanced Biosafety Level 2 Containment. Contact your local institutional biosafety office for accurate regional information.