TMB Substrate Solution

Abcam plc

Revision date : 2018-09-04

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GHS07
Health risk rating 2
Safety risk rating 1
Environmental risk rating 1

Note: Ingredients listed on restricted chemical lists

EC/CAS

55965-84-9

Name of the chemical

Mixture of 5-chloro-2-methyl-2H- isothiazol-3-one (EINECS 247-500-7) and 2-methyl-2H-isothiazol-3-one (EINECS 220-239-6)

Concentration

<0.0015

General Information

Version

6

Revision date

2018-09-04

Product name

TMB Substrate Solution

CAS No.

55965-84-9

1.2.1 Relevant identified uses

For research use only

supplier name

Abcam plc

Emergency telephone

+44 (0)1223 696000

Icons in SDS

GHS07

Company Information

company name

Abcam plc

e-mail address of the competent person responsible for the Safety Data Sheet

technical@abcam.com

GHS Information

Signal word

Warning

Section 2

SECTION 2: Hazards identification

Regulation (EC) No. 1272/2008 Classification of the substance or mixture

2.2 Label elements

Not dangerous

Precautionary statements

P280 - Wear protective gloves/ protective clothing

Further information

No information available

2.1 Classification of the substance or mixture

GHS / CLP - Regulation (EC) No 1272/2008 Ozone Not applicable 2.2 Label elements Not dangerous Precautionary Statements - EU (§28, 1272/2008) P280 - Wear protective gloves/ protective clothing 2.3 Other information No information available 3. COMPOSITION/INFORMATION ON INGREDIENTS 3.1 Substances Chemical Name EC-No CAS-No Weight % Classification (Reg. REACH Registration 1272/2008) Number Proclin - 55965-84-9 <0.0015 Skin Corr. 1B (H314) - Eye Dam. 1 (H318) Skin Sens. 1 (H317) Acute Tox. 3 (H301) Acute Tox. 3 (H311) Acute Tox. 3 (H331) Aquatic Acute 1 (H400) Aquatic Chronic 1 (H410) For the full text of the H-Statements mentioned in this Section, see Section 16 4. FIRST AID MEASURES 4.1 Description of first aid measures Eye contact Immediately flush with plenty of water. After initial flushing, remove any contact lenses and continue flushing for at least 15 minutes. Skin contact Wash off immediately with soap and plenty of water while removing all contaminated clothes and shoes. Ingestion Clean mouth with water. Drink plenty of water. Inhalation Move to fresh air. 4.2 Most important symptoms and effects, both acute and delayed Main symptoms see section 2.2. 4.3 Indication of any immediate medical attention and special treatment needed Notes to physician Treat symptomatically. 5. FIRE-FIGHTING MEASURES 5.1 Extinguishing media Suitable extinguishing media Use extinguishing measures that are appropriate to local circumstances and the surrounding environment. Extinguishing media which shall not be used for safety reasons No information available. 5.2 Special hazards arising from the substance or mixture Special hazard None in particular. 5.3 Advice for fire-fighters Special protective equipment for fire-fighters As in any fire, wear self-contained breathing apparatus and full protective gear. 6. ACCIDENTAL RELEASE MEASURES 6.1 Personal precautions, protective equipment and emergency procedures Ensure adequate ventilation. See Section 12 for additional information. 6.2 Environmental precautions Prevent further leakage or spillage if safe to do so. 6.3 Methods and materials for containment and cleaning up Soak up with inert absorbent material (e.g. sand, silica gel, acid binder, universal binder, sawdust). 7. HANDLING AND STORAGE 7.1 Precautions for safe handling Ensure adequate ventilation. 7.2 Conditions for safe storage, including any incompatibilities Keep container tightly closed in a dry and well-ventilated place. 7.3 Specific end uses Specific use(s) No information available. Exposure scenario No information available. 8. EXPOSURE CONTROLS/PERSONAL PROTECTION 8.1 Control parameters Exposure limits National occupational exposure limits Derived No Effect Level No information available Predicted No Effect Concentration No information available 8.2 Exposure controls Engineering measures Ensure adequate ventilation, especially in confined areas. Personal protective equipment Eye protection Tightly fitting safety goggles. Use equipment for eye protection tested and approved under appropriate government standards such as NIOSH (US) or EN 166(EU). Hand protection Protective gloves. Please observe the instructions regarding permeability and breakthrough time which are provided by the supplier of the gloves. Also take into consideration the specific local conditions under which the product is used, such as the danger of cuts, abrasion. Skin and body protection Long sleeved clothing. Respiratory protection No special protective equipment required. Thermal hazards No information available Hygiene measures Handle in accordance with good industrial hygiene and safety practice. Environmental exposure controls No information available. 9. PHYSICAL AND CHEMICAL PROPERTIES 9.1 Information on basic physical and chemical properties Physical State @20°C No information available Appearance No information available Odor No information available Property Values Note pH No information available Melting/freezing point No information available Boiling point/boiling range No information available Flash Point No information available Evaporation rate No information available Flammability (solid, gas) No information available Flammability Limits in Air upper flammability limit lower flammability limit Vapor pressure No information available Vapor density No information available Relative density No information available Water solubility No information available Solubility in other solvents No information available Partition coefficient: n-octanol/water No information available Autoignition temperature No information available Decomposition temperature No information available Viscosity, kinematic No information available Explosive properties No information available 9.2 Other information VOC Content(%) No information available 10. STABILITY AND REACTIVITY 10.1 Reactivity No information available. 10.2 Chemical stability Stable under normal conditions. 10.3 Precautionary Statements None under normal processing. 10.4 Conditions to avoid Heat, flames and sparks 10.5 Incompatible materials None in particular 10.6 Hazardous decomposition products None under normal use conditions. 11. TOXICOLOGICAL INFORMATION 11.1 Information on toxicological effects Acute toxicity Product Information Product does not present an acute toxicity hazard based on known or supplied information Inhalation There is no data available for this product. Eye contact There is no data available for this product. Skin contact There is no data available for this product. Ingestion There is no data available for this product. Chemical Name LD50 Oral LD50 Dermal LC50 Inhalation Proclin 53 mg/kg ( Rat ) Chronic toxicity Corrosivity No information available. Sensitization No information available. Neurological effects No information available. Reproductive toxicity No information available. Mutagenic effects No information available. Target Organ Effects No information available. 12. ECOLOGICAL INFORMATION 12.1 Toxicity Ecotoxicity effects As supplied, the preparation is not expected to present significant adverse environmental effects. 12.2 Persistence and degradability No information available. 12.3 Bioaccumulative potential No information available. 12.4 Mobility in soil No information available. 12.5 Results of PBT and vPvB assessment No information available. 12.6 Other adverse effects No information available. 13. DISPOSAL CONSIDERATIONS 13.1 Waste Treatment Methods Waste from residues / unused Dispose of in accordance with local regulations. products Contaminated packaging Empty containers should be taken to an approved waste handling site for recycling or disposal. 14. TRANSPORT INFORMATION ADR Not dangerous goods IATA Not dangerous goods DOT Not dangerous goods 15. REGULATORY INFORMATION 15.1 Safety, Health and Environmental Regulations/Legislation Specific for the Substance or Mixture No information available. 15.2 Chemical Safety Assessment No information available. 16. OTHER INFORMATION Full text of H-Statements referred to under sections 2 and 3 H301 + H311 + H331 - Toxic if swallowed, in contact with skin or if inhaled H314 - Causes severe skin burns and eye damage H317 - May cause an allergic skin reaction H318 - Causes serious eye damage H400 - Very toxic to aquatic life H410 - Very toxic to aquatic life with long lasting effects Revision Date 04-Sep-2018 Revision Note Not applicable. This safety data sheet complies with the requirements of Regulation (EC) No. 1907/2006 Disclaimer The information provided in this Safety Data Sheet is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guidance for safe handling, use, processing, storage, transportation, disposal and release and is not to be considered a warranty or quality specification. The information relates only to the specific material designated and may not be valid for such material used in combination with any other materials or in any process, unless specified in the text. End of SDS

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