Temozolomide, DNA alkylating/methylating chemotherapeutic agent

Hazard statements (CLP)

H300, H315, H319, H335, H340, H350, H360, H372

Code

Statements

H300

Fatal if swallowed

SECTION 2: Hazards identification

GHS Classification Acute toxicity - Oral Category 2 - (H300) Skin corrosion/irritation Category 2 - (H315) Serious eye damage/eye irritation Category 2 - (H319) Germ cell mutagenicity Category 1B - (H340) Carcinogenicity Category 1B - (H350) Reproductive toxicity Category 1B - (H360) Specific target organ toxicity (single exposure) Category 3 - (H335) Specific target organ toxicity (repeated exposure) Category 1 - (H372) Label elements

Signal word

DANGER Hazard statements H300 - Fatal if swallowed H315 - Causes skin irritation H319 - Causes serious eye irritation H335 - May cause respiratory irritation H340 - May cause genetic defects H350 - May cause cancer H360 - May damage fertility or the unborn child H372 - Causes damage to organs through prolonged or repeated exposure Precautionary Statements - Prevention Obtain special instructions before use Do not handle until all safety precautions have been read and understood Wear protective gloves/clothing and eye/face protection Wash face, hands and any exposed skin thoroughly after handling Do not eat, drink or smoke when using this product Use only outdoors or in a well-ventilated area Do not breathe dust/fume/gas/mist/vapours/spray Precautionary Statements - Response IF exposed or concerned: Get medical advice/attention IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing If eye irritation persists: Get medical advice/attention IF ON SKIN: Wash with plenty of water and soap If skin irritation occurs: Get medical advice/attention Take off contaminated clothing and wash it before reuse IF INHALED: Remove person to fresh air and keep comfortable for breathing Call a doctor if you feel unwell IF SWALLOWED: Immediately call a doctor Rinse mouth Precautionary Statements - Storage Store locked up Store in a well-ventilated place. Keep container tightly closed

Precautionary statements

Disposal Dispose of contents/container to an approved waste disposal plant

Other hazards which do not result in classification

Caution - substance not yet tested completely.

2.1 Classification of the substance or mixture

Category 2 - (H300) Skin corrosion/irritation Category 2 - (H315) Serious eye damage/eye irritation Category 2 - (H319) Germ cell mutagenicity Category 1B - (H340) Carcinogenicity Category 1B - (H350) Reproductive toxicity Category 1B - (H360) Specific target organ toxicity (single exposure) Category 3 - (H335) Specific target organ toxicity (repeated exposure) Category 1 - (H372) Label elements