Disodium octaborate tetrahydrate

Hazard statements (CLP)

H360FD

Code

Statements

H360FD

May damage fertility; May damage the unborn child

SECTION 2: Hazards identification

According to Regulation (EC) No 1272/2008 [CLP Classification of the substance

Signal word

Danger

Hazard statements

H360FD: May damage fertility or the unborn child.

Precautionary statements

P201 Obtain special instructions before use. P202 Do not handle until all safety precautions have been read and understood. P280 Wear protective gloves/protective clothing/eye protection/face protection. P308+P313 If exposed or concerned: get medical advice/attention. P405 Store locked up. 2.2.2. According to REACH, Annex XVII Restricted to professional users

2.3 Other hazards

Emergency overview Etidot-67 is a white odourless, powder substance that is not flammable, combustible, or explosive, and has low acute oral and dermal toxicity.

Potential health effects

Inhalation is the most significant route of exposure in occupational and other settings. Dermal exposure is not usually a concern because Etidot-67 is poorly absorbed through intact skin. Inhalation Occasional mild irritation effects to nose and throat may occur from inhalation of Etidot-67 dusts at levels higher than 10 mg/m3. Eye contact Etidot-67 is non-irritating to eyes in normal industrial use. Skin contact Etidot-67 does not cause irritation to intact skin. Ingestion Products containing Etidot-67 are not intended for ingestion. Etidot-67 has low acute toxicity. Small amounts (e.g. a teaspoon) swallowed accidentally are not likely to cause effects; swallowing amounts larger than that may cause gastrointestinal symptoms. Reproductive/developmental Animal ingestion studies in several species, at high doses, indicate that borates cause reproductive and developmental effects [1]. A human study of occupational exposure to borate dust showed no adverse effect on reproduction. A recent epidemiological study and a peer reviewing report of the past epidemiological studies conducted in China didn’t show any negative effect of boron on human fertility [2]. A study conducted in Turkey with boron exposed mine workers showed that mean blood concentrations of the high exposure group is ~6 times and ~9 times lower than those of the highest no effect level of boron in blood with regard to developmental and reprotoxic effects (respectively) in rats. With those findings, no unfavourable effects of boron exposure on reproductive indicators are observed in humans [3, 4]. Potential ecological effects Large amounts of Etidot-67 can be harmful to plants and other species. Therefore, the product should only be used as part of a balanced plant nutrition program preferably after soil and/or tissue analysis. Accidental releases to the environment should be minimized. Signs and symptoms of exposure Symptoms of accidental over-exposure to Etidot-67 have been associated with ingestion or absorption through large areas of damaged skin. These may include nausea, vomiting, and diarrheal, with delayed effects of skin redness and peeling (see SECTION 11).

2.1 Classification of the substance or mixture

2.1.1. Classification according to CLP (1272/2008) Regulation of EU Repr. Cat. 1B; H360FD Generic concentrations limits : Repr. 1B; H360FD: C ≥0.3% H360FD: May damage fertility or the unborn child. Precautionary Statement Prevention : P201; P202; P280 Precautionary Statement Response : P308+P313 Precautionary Statement Storage : P405 Precautionary Statement Disposal : P501 2.1.2. Additional information