General Information
Revision date
2007-07-24
Product name
Aniline Buffer
Product Synonyms
Sodium phosphate buffer containing a small catalytic amount of aniline
CAS No.
10049-21-5
Emergency telephone
1-800-424-9300, +1-703-527-3887
Icons in SDS
Company Information
company name
1-703-527-3887(International)
Section 2
NFPA Ratings
Scale 0-4) Health = 3 Fire = 2 Reactivity = 1
Health hazards
Aniline is toxic and dangerous for the environment. Toxic by inhalation, in contact with skin and if swallowed. Irritating to respritatory system and skin. Limited evidence of a carcinogenic effect. Serious risk of damage to eyes. May cause skin sensitization by skin contact. Danger of serious damage to health on prolonged exposure through inhalation, skin contact, or if swallowed. Possible risk of irreversible effects. Very toxic to aquatic organisms. Aniline is readily absorbed through the skin. Causes cyanosis. Target organs kidneys, bladder. Possible carcinogen (US). A. Emergency Overview: Information Pertaining To Particular Dangers for Man And Environment: Not known Physical Appearance: Clear liquid
Potential Acute Health Effects
for Aniline Acute Eye: Causes severe eye irritation. May cause lacrimation (tearing), blurred vision, and photophobia. May cause chemical conjunctivitis and corneal damage. Acute Skin: Causes moderate skin irritation. Readily absorbed through skin. Harmful if absorbed through the skin. May cause skin sensitization,an allergic reaction, which becomes evident upon re-exposure to this material. Acute Ingestion: Harmful if swallowed. Causes gastrointestinal irritation with nausea, vomiting and diarrhea. May cause effects similar to those of acute inhalation. May cause central nervous system depression, convulsions, coma, and possible death due to respiratory paralysis. May cause cardiac effects such as heart blocks, arrhythmias, shock and possible death due to cardiovascular collapse. Alcohol can intensify the ability of aniline to induce methemoglobinem Acute Inhalation: Effects may be delayed. Causes respiratory tract irritation. May cause methemoglobinemia, cyanosis (bluish discoloration of skin due to deficient oxygenation of the blood), convulsions, tachycardia, dyspnea (labored breathing), and death. Aspiration may lead to pulmonary edema. Chronic: May cause liver and kidney damage. May cause fetal effects. Repeated exposure may cause sensitization dermatitis. Chronic exposure may cause hemolysis of the red blood cells followed by stimulation of the bone marrow. Laboratory experiments have resulted in mutagenic effects. May cause cyanosis - a blue-gray coloring of the skin and lips caused by a lack of oxygen. Animal studies have reported the development of tumors.
Potential chronic health
for Aniline May cause liver and kidney damage. May cause fetal effects. Repeated exposure may cause sensitization dermatitis. Chronic exposure may cause hemolysis of the red blood cells followed by stimulation of the bone marrow. Laboratory experiments have resulted in mutagenic effects. May cause cyanosis - a blue-gray coloring of the skin and lips caused by a lack of oxygen. Animal studies have reported the development of tumors.